Human transition milk was sampled from 88 mothers at the Faroe Islands, where the seafood diet includes pilot whale meat and blubber. Milk mercury concentrations (median, 2.45 micrograms/liter) were significantly associated with mercury concentrations in cord blood and with the frequency of pilot whale dinners during pregnancy. Milk selenium concentrations (mean, 19.1 micrograms/liter) correlated significantly with concentrations in cord blood but not with seafood consumption. Arsenic concentrations were very low. Twenty-four of the milk samples were separated into four pools based on fish intake and milk mercury concentrations.

The polychlorinated biphenyl (PCB) concentrations (1.8-3.5 micrograms/g lipid) were high and mainly due to congener numbers 153, 180, and 138. One pool contained a congener 77 concentration of 1380 ppt, which is the highest ever reported in a human specimen for a coplanar PCB. This analysis shows that national exposure estimates are most influenced by reported concentrations in imported tuna, swordfish, and shrimp; Pacific pollock; and Atlantic crabs. Collecting additional mercury concentration data for these seafood categories would improve the accuracy of national exposure estimates.

The highest PCB concentrations were seen in the pools from women who had eaten frequent whale dinners and whose milk contained high mercury concentrations. The concentrations of chlorinated dibenzo-p-dioxins and furans were not similarly elevated. Given the advantages associated with breast-feeding, advice to nursing mothers in this population should take into regard the possible risks associated with long-term exposure to milk contaminants. Per capita mercury intake rates calculated using FDA mercury data differ significantly from those based on mercury concentration data for each supply area and intakes calculated for the 90th percentile of mercury concentrations. Differences in reported mercury concentrations can significantly affect per capita mercury intake estimates, pointing to the importance of spatially refined mercury concentration data.

Negative confounding in the evaluation of toxicity: the case of methylmercury in fish and seafood.

In observational studies, the presence of confounding [corrected] can distort the true association between an exposure and a toxic-effect outcome, if the confounding variable is not controlled for in the study design or analysis phase. While confounding is often assumed to occur in the same direction as the toxicant exposure, the relationship between the benefits and risks associated with fish and seafood consumption is a classic example of negative confounding: the exposure to methylmercury occurs with fish and seafood, which are also associated with beneficial nutrients, and the signs of mercury toxicity [corrected]

Mercury and nutrients may affect the same epidemiological outcomes, but most studies addressing one of them have ignored the potential for negative confounding by the other. This article reviews the existing evidence of effects of both nutrient and contaminant intakes as predictors of neurodevelopmental and cardiovascular outcomes. Substantial underestimation of the effects of mercury toxicity and of fish benefits occurs from the lack of confounder adjustment and imprecision of the exposure parameters. Given this inherent bias in observational studies, regulatory agencies should reconsider current dietary advice in order to provide better guidance to consumers in making prudent choices to maintain a nutritious diet with seafood that is low in mercury concentrations.

This review summarizes and discusses the current understanding of human exposure to cyanobacterial toxins in “seafood” collected from freshwater and coastal areas. The review consists of three parts: (a) the existing literature on concentrations of cyanobacterial toxins in seafood is reviewed, and the likelihood of bioaccumulation discussed; (b) we derive cyanotoxin doses likely to occur through seafood consumption and propose guideline values for seafood and compare these to guidelines for drinking water; and (c) we discuss means to assess, control or mitigate the risks of exposure to cyanotoxins through seafood consumption.

This is discussed in the context of two specific procedures, the food specific HACCP-approach and the water-specific Water Safety Plan approach by the WHO. Risks of exposure to cyanotoxins in food are sometimes underestimated. Risk assessments should acknowledge this and investigate the partitioning of exposure between drinking-water and food, which may vary depending on local circumstances. Attention should also be paid to the occurrence of negative confounding in other connections.

 Relation of a seafood diet to mercury, selenium, arsenic, and polychlorinated biphenyl and other organochlorine concentrations in human milk.

Epidemic cholera in Ecuador: multidrug-resistance and transmission by water and seafood.

To determine risk factors for cholera in an epidemic-disease area in South America, a case-control investigation was performed in Guayaquil, Ecuador, in July 1991. Residents>> 5 years old who were hospitalized for treatment of acute, watery diarrhoea and two matched controls for each were interviewed regarding sources of water and food, and eating, drinking, and hygienic habits. Interviewers inspected homes of case-patients and controls to document water treatment, food-handling, and hygienic practices. Faecal specimens and shellfish were cultured for Vibrio cholerae O 1. ( Maxanim RT-PCR detection)

pGB BAX siRNA Vector Mix

9513-20
EUR 610

pGB BAX siRNA Vector Mix

9513-60
EUR 1055

pGB BID siRNA Vector Mix

9515-20
EUR 610

pGB BID siRNA Vector Mix

9515-60
EUR 1055

pGB Hsp90 siRNA Vector Mix

9518-20
EUR 610

pGB Hsp90 siRNA Vector Mix

9518-60
EUR 1055

pGB Bcl-2 siRNA Vector Mix

9514-20
EUR 610

pGB Bcl-2 siRNA Vector Mix

9514-60
EUR 1055

pGB CIAP-1 siRNA Vector Mix

9516-20
EUR 610

pGB CIAP-1 siRNA Vector Mix

9516-60
EUR 1055

pGB CIAP-2 siRNA Vector Mix

9517-20
EUR 610

pGB CIAP-2 siRNA Vector Mix

9517-60
EUR 1055

siRNA Cloning Vector (pGB)

9500-20
EUR 294

Control siRNA Vector (pGB-control)

9500C-20
EUR 338

pGB Caspase-1 siRNA Vector

9501-20
EUR 610

pGB Caspase-1 siRNA Vector

9501-60
EUR 1055

pGB Caspase-3 siRNA Vector

9503-20
EUR 610

pGB Caspase-3 siRNA Vector

9503-60
EUR 1055

pGB Caspase-8 siRNA Vector

9508-20
EUR 610

pGB Caspase-8 siRNA Vector

9508-60
EUR 1055

pGB Caspase-9 siRNA Vector

9509-20
EUR 610

pGB Caspase-9 siRNA Vector

9509-60
EUR 1055

Human Apoptosis Inducing Factor (AIF) ELISA Kit

DLR-AIF-Hu-48T 48T
EUR 498
Description: A sandwich quantitative ELISA assay kit for detection of Human Apoptosis Inducing Factor (AIF) in samples from serum, plasma, tissue homogenates or other biological fluids.

Human Apoptosis Inducing Factor (AIF) ELISA Kit

DLR-AIF-Hu-96T 96T
EUR 647
Description: A sandwich quantitative ELISA assay kit for detection of Human Apoptosis Inducing Factor (AIF) in samples from serum, plasma, tissue homogenates or other biological fluids.

Rat Apoptosis Inducing Factor (AIF) ELISA Kit

DLR-AIF-Ra-48T 48T
EUR 528
Description: A sandwich quantitative ELISA assay kit for detection of Rat Apoptosis Inducing Factor (AIF) in samples from serum, plasma, tissue homogenates or other biological fluids.

Rat Apoptosis Inducing Factor (AIF) ELISA Kit

DLR-AIF-Ra-96T 96T
EUR 690
Description: A sandwich quantitative ELISA assay kit for detection of Rat Apoptosis Inducing Factor (AIF) in samples from serum, plasma, tissue homogenates or other biological fluids.

Human Apoptosis Inducing Factor (AIF) ELISA Kit

RD-AIF-Hu-48Tests 48 Tests
EUR 500

Human Apoptosis Inducing Factor (AIF) ELISA Kit

RD-AIF-Hu-96Tests 96 Tests
EUR 692

Rat Apoptosis Inducing Factor (AIF) ELISA Kit

RD-AIF-Ra-48Tests 48 Tests
EUR 534

Rat Apoptosis Inducing Factor (AIF) ELISA Kit

RD-AIF-Ra-96Tests 96 Tests
EUR 742

Human Apoptosis Inducing Factor (AIF) ELISA Kit

RDR-AIF-Hu-48Tests 48 Tests
EUR 522

Human Apoptosis Inducing Factor (AIF) ELISA Kit

RDR-AIF-Hu-96Tests 96 Tests
EUR 724

Rat Apoptosis Inducing Factor (AIF) ELISA Kit

RDR-AIF-Ra-48Tests 48 Tests
EUR 558

Rat Apoptosis Inducing Factor (AIF) ELISA Kit

RDR-AIF-Ra-96Tests 96 Tests
EUR 776

AIF/ Rat AIF ELISA Kit

ELA-E1064r 96 Tests
EUR 886

AIF Antibody

BF0591 200ul
EUR 376
Description: AIF antibody detects endogenous levels of total AIF.

anti-AIF

YF-PA16113 50 ul
EUR 363
Description: Mouse polyclonal to AIF

anti-AIF

YF-PA16114 50 ug
EUR 363
Description: Mouse polyclonal to AIF

anti-AIF

YF-PA16115 100 ug
EUR 403
Description: Rabbit polyclonal to AIF

anti-AIF

YF-PA25270 50 ul
EUR 334
Description: Mouse polyclonal to AIF

AIF antibody

70R-11690 100 ug
EUR 403
Description: Rabbit polyclonal AIF antibody

AIF antibody

70R-21441 50 ul
EUR 435
Description: Rabbit polyclonal AIF antibody

AIF Antibody

3202-100
EUR 316

AIF Antibody

3202-30T
EUR 146

AIF Antibody

24095-100ul 100ul
EUR 390

AIF Antibody

24105-100ul 100ul
EUR 390

AIF Antibody

24114-100ul 100ul
EUR 390

AIF Antibody

48692-100ul 100ul
EUR 333

AIF Antibody

48692-50ul 50ul
EUR 239

AIF Blocking Peptide

BF0591-BP 1mg
EUR 195

AIF Blocking Peptide

33R-10667 50 ug
EUR 191
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of AIF antibody, catalog no. 70R-11690

AIF Blocking Peptide

3202BP-50
EUR 153

anti-AIF (4E7)

LF-MA30608 100 ul
EUR 527
Description: Mouse Monoclonal to AIF

Anti-AIF antibody

PAab00235 100 ug
EUR 355

AIF Rabbit mAb

A19536-100ul 100 ul
EUR 410

AIF Rabbit mAb

A19536-200ul 200 ul
EUR 571

AIF Rabbit mAb

A19536-20ul 20 ul
EUR 221

AIF Rabbit mAb

A19536-50ul 50 ul
EUR 287

Anti-AIF antibody

STJ99301 200 µl
EUR 197
Description: Mouse monoclonal to AIF.

AIF Conjugated Antibody

C48692 100ul
EUR 397

anti- AIF antibody

FNab00235 100µg
EUR 505.25
Description: Antibody raised against AIF

AIF Rabbit mAb

A19536 20 μL
EUR 15

Canine Pepsin B, PGB ELISA KIT

ELI-21572d 96 Tests
EUR 928

Porcine Pepsin B, PGB ELISA KIT

ELI-37737p 96 Tests
EUR 928

dNTP Mix

G010 250 ul 10 mM each
EUR 73

dNTP Mix

G128 500 ul 10 mM each
EUR 82

dNTP Mix

G129 1.0 ml 10 mM each
EUR 101

NTP Mix

G943 250 ul 25 mM each
EUR 78

NTP Mix

G944 500 ul 25 mM each
EUR 97

NTP Mix

G945 1.0 ml 25 mM each
EUR 130

PCR Mix

L5051100 2.5 ml
EUR 107
Description: Premade ready to use kits will always come in handy. Get your experiment done right form the first try by using a validated kit with perfectly balanced reagents proportions and compatibility and by following a clear protocol.

dNTP Mix

K6011105-100 100 ul (10 mM each)
EUR 86
Description: Premade ready to use kits will always come in handy. Get your experiment done right form the first try by using a validated kit with perfectly balanced reagents proportions and compatibility and by following a clear protocol.

dNTP Mix

K6011105-1000 1000 ul (10 mM each)
EUR 201
Description: Premade ready to use kits will always come in handy. Get your experiment done right form the first try by using a validated kit with perfectly balanced reagents proportions and compatibility and by following a clear protocol.

dNTP Mix

K6011105-200 200 ul (10 mM each)
EUR 93
Description: Premade ready to use kits will always come in handy. Get your experiment done right form the first try by using a validated kit with perfectly balanced reagents proportions and compatibility and by following a clear protocol.

dNTP Mix

K6011105-400 400 ul (10 mM each)
EUR 116
Description: Premade ready to use kits will always come in handy. Get your experiment done right form the first try by using a validated kit with perfectly balanced reagents proportions and compatibility and by following a clear protocol.

AIF ELISA KIT|Human

EF006581 96 Tests
EUR 689

AIF recombinant monoclonal antibody

A5256 100ul X 3
EUR 595
Description: A recombinant monoclonal antibody from rabbit against human AIF for WB, IHC, IF,ELISA

Sheep AIF ELISA Kit

ESA0535 96Tests
EUR 521

Mouse AIF ELISA Kit

EMA0535 96Tests
EUR 521

Monkey AIF ELISA Kit

EMKA0535 96Tests
EUR 521

Porcine AIF ELISA Kit

EPA0535 96Tests
EUR 521

Rat AIF ELISA Kit

ERA0535 96Tests
EUR 521

Rabbit AIF ELISA Kit

ERTA0535 96Tests
EUR 521

Anti-AIF/AIFM1 Antibody

PA2232 100ug/vial
EUR 334

Anti-AIF/AIFM1 Antibody

PB9366 100ug/vial
EUR 334

AIF-M1 Polyclonal Antibody

ES1615-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against AIF-M1 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

AIF-M1 Polyclonal Antibody

ES1615-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against AIF-M1 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

Anserini AIF ELISA Kit

EAA0535 96Tests
EUR 521

Goat AIF ELISA Kit

EGTA0535 96Tests
EUR 521

Canine AIF ELISA Kit

ECA0535 96Tests
EUR 521

Chicken AIF ELISA Kit

ECKA0535 96Tests
EUR 521

Human AIF ELISA Kit

EHA0535 96Tests
EUR 521

Bovine AIF ELISA Kit

EBA0535 96Tests
EUR 521

AIF-M1 Polyclonal Antibody

ABP50616-003ml 0.03ml
EUR 158
Description: A polyclonal antibody for detection of AIF-M1 from Human, Mouse, Rat. This AIF-M1 antibody is for WB , IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the N-terminal region of human AIF-M1 at AA range: 30-110

AIF-M1 Polyclonal Antibody

ABP50616-01ml 0.1ml
EUR 289
Description: A polyclonal antibody for detection of AIF-M1 from Human, Mouse, Rat. This AIF-M1 antibody is for WB , IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the N-terminal region of human AIF-M1 at AA range: 30-110

AIF-M1 Polyclonal Antibody

ABP50616-02ml 0.2ml
EUR 414
Description: A polyclonal antibody for detection of AIF-M1 from Human, Mouse, Rat. This AIF-M1 antibody is for WB , IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the N-terminal region of human AIF-M1 at AA range: 30-110

Anti-AIF-M1 antibody

STJ91514 200 µl
EUR 197
Description: Rabbit polyclonal to AIF-M1.

Anti-AIF-M1 antibody

STJ97819 100 µl
EUR 234
Description: Mouse monoclonal to AIF-M1.

AIF-M1 Polyclonal Antibody

40560-100ul 100ul
EUR 252

AIF-M1 Polyclonal Antibody

40560-50ul 50ul
EUR 187

Recombinant Apoptosis Inducing Factor (AIF)

4-RPB064Hu01
  • EUR 476.32
  • EUR 230.00
  • EUR 1511.20
  • EUR 570.40
  • EUR 1040.80
  • EUR 382.00
  • EUR 3628.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Apoptosis Inducing Factor expressed in: E.coli

Anti-AIF Rabbit Monoclonal Antibody

M01571 100ug/vial
EUR 397
Description: Rabbit Monoclonal AIF Antibody. Validated in IP, IF, WB and tested in Human, Mouse, Rat.

Anti-AIF Antibody (monoclonal, 2I5)

M01571-1 100ug/vial
EUR 334

Guinea Pig AIF ELISA Kit

EGA0535 96Tests
EUR 521

Apoptosis Inducing Factor (AIF) Antibody

20-abx102410
  • EUR 411.00
  • EUR 133.00
  • EUR 1149.00
  • EUR 565.00
  • EUR 314.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Apoptosis Inducing Factor (AIF) Antibody

abx011979-100ul 100 ul
EUR 411

[KO Validated] AIF Rabbit pAb

A2568-100ul 100 ul
EUR 410

[KO Validated] AIF Rabbit pAb

A2568-200ul 200 ul
EUR 571

[KO Validated] AIF Rabbit pAb

A2568-20ul 20 ul
EUR 221

[KO Validated] AIF Rabbit pAb

A2568-50ul 50 ul
EUR 287

Apoptosis Inducing Factor (AIF) Antibody

20-abx171293
  • EUR 815.00
  • EUR 425.00
  • 1 mg
  • 200 ug

Apoptosis Inducing Factor (AIF) Antibody

20-abx171294
  • EUR 871.00
  • EUR 453.00
  • 1 mg
  • 200 ug

Apoptosis Inducing Factor (AIF) Antibody

abx230235-100ug 100 ug
EUR 481

Apoptosis Inducing Factor (AIF) Antibody

20-abx175443
  • EUR 1247.00
  • EUR 592.00
  • 1 mg
  • 200 ug

Monoclonal AIF Antibody, Clone: 4E7

APR14886G 0.1ml
EUR 528
Description: A Monoclonal antibody against Human AIF. The antibodies are raised in Mouse and are from clone 4E7. This antibody is applicable in WB and IHC, FC, ICC, E

AIF ELISA Kit (Human) (OKDD00119)

OKDD00119 96 Wells
EUR 923
Description: Description of target: This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause combined oxidative phosphorylation deficiency 6 (COXPD6), a severe mitochondrial encephalomyopathy, as well as Cowchock syndrome, also known as X-linked recessive Charcot-Marie-Tooth disease-4 (CMTX-4), a disorder resulting in neuropathy, and axonal and motor-sensory defects with deafness and mental retardation. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 10.;Species reactivity: Human;Application: ;Assay info: Quantitative Sandwich ELISA;Sensitivity: < 0.064 ng/mL

Polyclonal AIFM1 / AIF / PDCD8 Antibody

APG01630G 0.1ml
EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human AIFM1 / AIF / PDCD8 . This antibody is tested and proven to work in the following applications:

AIF-M1 Polyclonal Conjugated Antibody

C40560 100ul
EUR 397

Individual Reaction Mix

G065-X 200 reactions
EUR 167

Glucose Nutrient Mix

109 150 g
EUR 67

Green Taq Mix

P131-01 5 ml
EUR 119

Green Taq Mix

P131-02 15 ml
EUR 150

Green Taq Mix

P131-03 50 ml
EUR 248

Isolates were tested for susceptibility to a variety of antimicrobial agents. Drinking unboiled water (odds ratio [OR] = 4.0, confidence interval [CI] = 1.8-7.5), drinking a beverage from a street vendor (OR = 2.8, CI = 1.3-5.9), eating raw seafood (OR = 3.4, CI = 1.4-11.5), and eating cooked crab (OR = 5.1, CI = 1.4-19.2) were associated with illness. Always boiling drinking water at home (OR = 0.5, CI = 0.2-0.9) was protective against illness. The presence of soap in either the kitchen (OR = 0.3, CI = 0.2-0.8) or bathroom (OR = 0.4, CI = 0.2-0.9) at home was also protective. V. cholerae O 1 was recovered from a pooled sample of a bivalve mollusc and from 68% of stool samples from case-patients. Thirty-six percent of the isolates from stool specimens were resistant to multiple antimicrobial agents.

Specific prevention measures may prevent transmission through these vehicles in the future. The appearance of antimicrobial resistance suggests the need for changes in current methods of prevention and treatment.