Human transition milk was sampled from 88 mothers at the Faroe Islands, where the seafood diet includes pilot whale meat and blubber. Milk mercury concentrations (median, 2.45 micrograms/liter) were significantly associated with mercury concentrations in cord blood and with the frequency of pilot whale dinners during pregnancy. Milk selenium concentrations (mean, 19.1 micrograms/liter) correlated significantly with concentrations in cord blood but not with seafood consumption. Arsenic concentrations were very low. Twenty-four of the milk samples were separated into four pools based on fish intake and milk mercury concentrations.
The polychlorinated biphenyl (PCB) concentrations (1.8-3.5 micrograms/g lipid) were high and mainly due to congener numbers 153, 180, and 138. One pool contained a congener 77 concentration of 1380 ppt, which is the highest ever reported in a human specimen for a coplanar PCB. This analysis shows that national exposure estimates are most influenced by reported concentrations in imported tuna, swordfish, and shrimp; Pacific pollock; and Atlantic crabs. Collecting additional mercury concentration data for these seafood categories would improve the accuracy of national exposure estimates.
The highest PCB concentrations were seen in the pools from women who had eaten frequent whale dinners and whose milk contained high mercury concentrations. The concentrations of chlorinated dibenzo-p-dioxins and furans were not similarly elevated. Given the advantages associated with breast-feeding, advice to nursing mothers in this population should take into regard the possible risks associated with long-term exposure to milk contaminants. Per capita mercury intake rates calculated using FDA mercury data differ significantly from those based on mercury concentration data for each supply area and intakes calculated for the 90th percentile of mercury concentrations. Differences in reported mercury concentrations can significantly affect per capita mercury intake estimates, pointing to the importance of spatially refined mercury concentration data.
Negative confounding in the evaluation of toxicity: the case of methylmercury in fish and seafood.
In observational studies, the presence of confounding [corrected] can distort the true association between an exposure and a toxic-effect outcome, if the confounding variable is not controlled for in the study design or analysis phase. While confounding is often assumed to occur in the same direction as the toxicant exposure, the relationship between the benefits and risks associated with fish and seafood consumption is a classic example of negative confounding: the exposure to methylmercury occurs with fish and seafood, which are also associated with beneficial nutrients, and the signs of mercury toxicity [corrected]
Mercury and nutrients may affect the same epidemiological outcomes, but most studies addressing one of them have ignored the potential for negative confounding by the other. This article reviews the existing evidence of effects of both nutrient and contaminant intakes as predictors of neurodevelopmental and cardiovascular outcomes. Substantial underestimation of the effects of mercury toxicity and of fish benefits occurs from the lack of confounder adjustment and imprecision of the exposure parameters. Given this inherent bias in observational studies, regulatory agencies should reconsider current dietary advice in order to provide better guidance to consumers in making prudent choices to maintain a nutritious diet with seafood that is low in mercury concentrations.
This review summarizes and discusses the current understanding of human exposure to cyanobacterial toxins in “seafood” collected from freshwater and coastal areas. The review consists of three parts: (a) the existing literature on concentrations of cyanobacterial toxins in seafood is reviewed, and the likelihood of bioaccumulation discussed; (b) we derive cyanotoxin doses likely to occur through seafood consumption and propose guideline values for seafood and compare these to guidelines for drinking water; and (c) we discuss means to assess, control or mitigate the risks of exposure to cyanotoxins through seafood consumption.
This is discussed in the context of two specific procedures, the food specific HACCP-approach and the water-specific Water Safety Plan approach by the WHO. Risks of exposure to cyanotoxins in food are sometimes underestimated. Risk assessments should acknowledge this and investigate the partitioning of exposure between drinking-water and food, which may vary depending on local circumstances. Attention should also be paid to the occurrence of negative confounding in other connections.
Epidemic cholera in Ecuador: multidrug-resistance and transmission by water and seafood.
To determine risk factors for cholera in an epidemic-disease area in South America, a case-control investigation was performed in Guayaquil, Ecuador, in July 1991. Residents>> 5 years old who were hospitalized for treatment of acute, watery diarrhoea and two matched controls for each were interviewed regarding sources of water and food, and eating, drinking, and hygienic habits. Interviewers inspected homes of case-patients and controls to document water treatment, food-handling, and hygienic practices. Faecal specimens and shellfish were cultured for Vibrio cholerae O 1. ( Maxanim RT-PCR detection)
pGB BAX siRNA Vector Mix |
9513-20 |
Biovision |
each |
EUR 732 |
pGB BAX siRNA Vector Mix |
9513-60 |
Biovision |
each |
EUR 1266 |
pGB BID siRNA Vector Mix |
9515-20 |
Biovision |
each |
EUR 732 |
pGB BID siRNA Vector Mix |
9515-60 |
Biovision |
each |
EUR 1266 |
pGB Hsp90 siRNA Vector Mix |
9518-20 |
Biovision |
each |
EUR 732 |
pGB Hsp90 siRNA Vector Mix |
9518-60 |
Biovision |
each |
EUR 1266 |
pGB Bcl-2 siRNA Vector Mix |
9514-20 |
Biovision |
each |
EUR 732 |
pGB Bcl-2 siRNA Vector Mix |
9514-60 |
Biovision |
each |
EUR 1266 |
pGB CIAP-1 siRNA Vector Mix |
9516-20 |
Biovision |
each |
EUR 732 |
pGB CIAP-1 siRNA Vector Mix |
9516-60 |
Biovision |
each |
EUR 1266 |
pGB CIAP-2 siRNA Vector Mix |
9517-20 |
Biovision |
each |
EUR 732 |
pGB CIAP-2 siRNA Vector Mix |
9517-60 |
Biovision |
each |
EUR 1266 |
siRNA Cloning Vector (pGB) |
9500-20 |
Biovision |
each |
EUR 352.8 |
pGB Caspase-1 siRNA Vector |
9501-20 |
Biovision |
each |
EUR 732 |
pGB Caspase-1 siRNA Vector |
9501-60 |
Biovision |
each |
EUR 1266 |
pGB Caspase-3 siRNA Vector |
9503-20 |
Biovision |
each |
EUR 732 |
pGB Caspase-3 siRNA Vector |
9503-60 |
Biovision |
each |
EUR 1266 |
pGB Caspase-8 siRNA Vector |
9508-20 |
Biovision |
each |
EUR 732 |
pGB Caspase-8 siRNA Vector |
9508-60 |
Biovision |
each |
EUR 1266 |
pGB Caspase-9 siRNA Vector |
9509-20 |
Biovision |
each |
EUR 732 |
pGB Caspase-9 siRNA Vector |
9509-60 |
Biovision |
each |
EUR 1266 |
Control siRNA Vector (pGB-control) |
9500C-20 |
Biovision |
each |
EUR 405.6 |
Green Kit. Baculovirus GFP vector. |
K20 |
AB Vector LLC |
1 Kit |
EUR 695 |
|
Description: Protein expression |
ProGreen. Baculovirus GFP marker vector. |
A1 |
AB Vector LLC |
25 ul |
EUR 420 |
|
Description: Protein expression |
pVL1393. General baculovirus plasmid vector. |
B1 |
AB Vector LLC |
50 ul |
EUR 340 |
|
Description: Protein expression |
ProEasy. Vector for easy construction of recombinant baculoviruses. |
A10S |
AB Vector LLC |
25 ul |
EUR 695 |
|
Description: Protein expression |
pAcAB3. Baculovirus plasmid vector for expression of up to 3 proteins. |
B2 |
AB Vector LLC |
50 ul |
EUR 420 |
|
Description: Protein expression |
pAB-bee. Baculovirus plasmid vector for secreted and transmembrane proteins. |
B3 |
AB Vector LLC |
50 ul |
EUR 495 |
|
Description: Protein expression |
ProFold-PDI. Baculovirus chaperone vector for expression of cysteine-rich proteins. |
A7 |
AB Vector LLC |
25 ul |
EUR 830 |
|
Description: Protein expression |
ProFold-C1. Baculovirus chaperone vector for expression of cytoplasmic and nuclear proteins. |
A2 |
AB Vector LLC |
25 ul |
EUR 830 |
|
Description: Protein expression |
ProFold-C2. Baculovirus chaperone vector for expression of cytoplasmic and nuclear proteins. |
A3 |
AB Vector LLC |
25 ul |
EUR 830 |
|
Description: Protein expression |
ProFold-ER1. Baculovirus chaperone vector for expression of secreted and membrane proteins. |
A4 |
AB Vector LLC |
25 ul |
EUR 830 |
|
Description: Protein expression |
C1 Kit. Baculovirus chaperone vectors for cytoplasmic and nuclear proteins. |
K21 |
AB Vector LLC |
1 Kit |
EUR 995 |
|
Description: Protein expression |
C2 Kit. Baculovirus chaperone vectors for cytoplasmic and nuclear proteins. |
K22 |
AB Vector LLC |
1 Kit |
EUR 995 |
|
Description: Protein expression |
ER1 Kit. Baculovirus chaperone vectors for expression of secreted and membrane proteins. |
K23 |
AB Vector LLC |
1 Kit |
EUR 995 |
|
Description: Protein expression |
ER1-bee Kit. Baculovirus chaperone vectors for expression of secreted and membrane proteins. |
K24 |
AB Vector LLC |
1 Kit |
EUR 995 |
|
Description: Protein expression |
pAB-bee-FH. FLAG and His tagging of secreted and transmembrane proteins in baculovirus system. |
B3FH |
AB Vector LLC |
50 ul |
EUR 495 |
|
Description: Protein expression |
pAB-bee-8xHis. His tagging of secreted and transmembrane proteins in baculovirus system. |
B3H |
AB Vector LLC |
50 ul |
EUR 495 |
|
Description: Protein expression |
pAB-6xHis. His tagging of cytoplasmic and nuclear proteins in baculovirus system. |
B4 |
AB Vector LLC |
50 ul |
EUR 295 |
|
Description: Protein expression |
pAB-GST. GST tagging of cytoplasmic and nuclear proteins in baculovirus system. |
B5 |
AB Vector LLC |
50 ul |
EUR 295 |
|
Description: Protein expression |
pAB-MBP. MBP tagging of cytoplasmic and nuclear proteins in baculovirus system. |
B6 |
AB Vector LLC |
50 ul |
EUR 395 |
|
Description: Protein expression |
pAB-6xHis-MBP. His and MBP tagging of cytoplasmic and nuclear proteins in baculovirus system. |
B7 |
AB Vector LLC |
50 ul |
EUR 495 |
|
Description: Protein expression |
pVL-GFP. GFP tagging of cytoplasmic and nuclear proteins in baculovirus system. |
B8 |
AB Vector LLC |
50 ul |
EUR 395 |
|
Description: Protein expression |
pVL-FH. Flag and His tagging of cytoplasmic and nuclear proteins in baculovirus system. |
B9 |
AB Vector LLC |
50 ul |
EUR 295 |
|
Description: Protein expression |
BV-p53. Recombinant baculovirus expressing p53 (wt). |
BV53 |
AB Vector LLC |
1 ml |
EUR 980 |
|
Description: Drug discovery, Transcription factors, baculovirus |
NC (negative control baculovirus) |
C13 |
AB Vector LLC |
1 ml |
EUR 195 |
|
Description: Protein expression |
GC (green control baculovirus expressing GFP) |
C14 |
AB Vector LLC |
1 ml |
EUR 195 |
|
Description: Protein expression |
GCP (green control plasmid for GFP expression) |
C15 |
AB Vector LLC |
50 ul |
EUR 145 |
|
Description: Protein expression |
BV-ADRA1D. Recombinant baculovirus expressing Adrenergic Receptor alpha 1D. |
GA11 |
AB Vector LLC |
1 ml |
EUR 499 |
|
Description: Drug discovery, GPCRs, baculovirus |
BV-ADRA2A. Recombinant baculovirus expressing Adrenergic Receptor alpha 2A. |
GA15 |
AB Vector LLC |
1 ml |
EUR 499 |
|
Description: Drug discovery, GPCRs, baculovirus |
BV-ADRA2C. Recombinant baculovirus expressing Adrenergic Receptor alpha 2C. |
GA19 |
AB Vector LLC |
1 ml |
EUR 499 |
|
Description: Drug discovery, GPCRs, baculovirus |
BV-ADRB2. Recombinant baculovirus expressing Adrenergic Receptor beta 2 |
GA23 |
AB Vector LLC |
1 ml |
EUR 499 |
|
Description: Drug discovery, GPCRs, baculovirus |
BV-ADRA1A. Recombinant baculovirus expressing Adrenergic Receptor alpha 1A (ADRA1A) |
GA3 |
AB Vector LLC |
1 ml |
EUR 499 |
|
Description: Drug discovery, GPCRs, baculovirus |
BV-ADRA1B. Recombinant baculovirus expressing Adrenergic Receptor alpha 1B. |
GA7 |
AB Vector LLC |
1 ml |
EUR 499 |
|
Description: Drug discovery, GPCRs, baculovirus |
BV-AGTR1. Recombinant baculovirus expressing angiotensin II receptor (AGTR1). |
GAT1 |
AB Vector LLC |
1 ml |
EUR 499 |
|
Description: Drug discovery, GPCRs, baculovirus |
BV-DRD1. Recombinant baculovirus expressing Dopamine receptor 1 (DRD1). |
GD3 |
AB Vector LLC |
1 ml |
EUR 499 |
|
Description: Drug discovery, GPCRs, baculovirus |
BV-DRD2. Recombinant baculovirus expressing Dopamine receptor 1 (DRD2). |
GD5 |
AB Vector LLC |
1 ml |
EUR 499 |
|
Description: Drug discovery, GPCRs, baculovirus |
BV-HRH1. Recombinant baculovirus expressing Histamine receptor (HRH1). |
GH41 |
AB Vector LLC |
1 ml |
EUR 499 |
|
Description: Drug discovery, GPCRs, baculovirus |
BV-HRH2. Recombinant baculovirus expressing Histamine receptor (HRH2). |
GH45 |
AB Vector LLC |
1 ml |
EUR 499 |
|
Description: Drug discovery, GPCRs, baculovirus |
BV-HRH3. Recombinant baculovirus expressing Histamine receptor (HRH3). |
GH49 |
AB Vector LLC |
1 ml |
EUR 499 |
|
Description: Drug discovery, GPCRs, baculovirus |
BV-HRH4. Recombinant baculovirus expressing Histamine receptor (HRH4). |
GH53 |
AB Vector LLC |
1 ml |
EUR 499 |
|
Description: Drug discovery, GPCRs, baculovirus |
BV-CHRM1. Recombinant baculovirus expressing Muscarinic acetylcholine receptor 1 (CHRM1). |
GM1 |
AB Vector LLC |
1 ml |
EUR 499 |
|
Description: Drug discovery, GPCRs, baculovirus |
BV-CHRM2. Recombinant baculovirus expressing Muscarinic acetylcholine receptor 2 (CHRM2). |
GM5 |
AB Vector LLC |
1 ml |
EUR 499 |
|
Description: Drug discovery, GPCRs, baculovirus |
BV-HTR1A. Recombinant baculovirus expressing 5-hydroxytryptamine (serotonin) receptor 1A. |
GS27 |
AB Vector LLC |
1 ml |
EUR 499 |
|
Description: Drug discovery, GPCRs, baculovirus |
BV-HTR1B. Recombinant baculovirus expressing 5-hydroxytryptamine (serotonin) receptor 1B. |
GS31 |
AB Vector LLC |
1 ml |
EUR 499 |
|
Description: Drug discovery, GPCRs, baculovirus |
BV-HTR1D. Recombinant baculovirus expressing 5-hydroxytryptamine (serotonin) receptor 1D. |
GS35 |
AB Vector LLC |
1 ml |
EUR 499 |
|
Description: Drug discovery, GPCRs, baculovirus |
BV-HTR1F. Recombinant baculovirus expressing 5-hydroxytryptamine (serotonin) receptor 1F. |
GS37 |
AB Vector LLC |
1 ml |
EUR 499 |
|
Description: Drug discovery, GPCRs, baculovirus |
BV-HTR2A. Recombinant baculovirus expressing 5-hydroxytryptamine (serotonin) receptor 2A. |
GS39 |
AB Vector LLC |
1 ml |
EUR 499 |
|
Description: Drug discovery, GPCRs, baculovirus |
BV-HTR2B. Recombinant baculovirus expressing 5-hydroxytryptamine (serotonin) receptor 2B. |
GS43 |
AB Vector LLC |
1 ml |
EUR 499 |
|
Description: Drug discovery, GPCRs, baculovirus |
BV-HTR2C. Recombinant baculovirus expressing 5-hydroxytryptamine (serotonin) receptor 2C. |
GS47 |
AB Vector LLC |
1 ml |
EUR 499 |
|
Description: Drug discovery, GPCRs, baculovirus |
BV-HTR5A. Recombinant baculovirus expressing 5-hydroxytryptamine (serotonin) receptor 5A. |
GS51 |
AB Vector LLC |
1 ml |
EUR 499 |
|
Description: Drug discovery, GPCRs, baculovirus |
BV-HTR7B. Recombinant baculovirus expressing 5-hydroxytryptamine (serotonin) receptor 7B. |
GS55 |
AB Vector LLC |
1 ml |
EUR 499 |
|
Description: Drug discovery, GPCRs, baculovirus |
FoldHelper-57P. Recombinant baculovirus expressing ERp57 and PDI. |
H17 |
AB Vector LLC |
1 ml |
EUR 295 |
|
Description: Protein expression |
FoldHelper-37. Recombinant baculovirus expressing cdc37. |
H18 |
AB Vector LLC |
1 ml |
EUR 395 |
|
Description: Protein expression |
FoldHelper-ER3. Recombinant baculovirus expressing human ER chaperones. |
H6 |
AB Vector LLC |
2 ml |
EUR 695 |
|
Description: Protein expression |
Controls Kit. Baculovirus controls. |
K26 |
AB Vector LLC |
1 Kit |
EUR 295 |
|
Description: Protein expression |
THRB-LBD. Purified GST-tagged human Thyroid hormone receptor beta ligand binding domain. Applications: Ligand-binding and coregulator displacement assays. |
N1A2 |
AB Vector LLC |
50 ug |
EUR 660 |
|
Description: Drug discovery, Nuclear receptors, purified recombinant protein |
RARA-LBD. Purified GST-tagged human Retinoic acid receptor alpha ligand binding domain. Applications: Ligand-binding and coregulator displacement assays. |
N1B1 |
AB Vector LLC |
50 ug |
EUR 498 |
|
Description: Drug discovery, Nuclear receptors, purified recombinant protein |
RARB-LBD. Purified GST-tagged human Retinoic acid receptor beta ligand binding domain. Applications: Ligand-binding and coregulator displacement assays. |
N1B2 |
AB Vector LLC |
50 ug |
EUR 420 |
|
Description: Drug discovery, Nuclear receptors, purified recombinant protein |
RARG-LBD. Purified GST-tagged human Retinoic acid receptor gamma ligand binding domain. Applications: Ligand-binding and coregulator displacement assays. |
N1B3 |
AB Vector LLC |
50 ug |
EUR 498 |
|
Description: Drug discovery, Nuclear receptors, purified recombinant protein |
PPARG-LBD. Purified GST-tagged human Peroxisome proliferator-activated receptor gamma ligand binding domain. Applications: Ligand-binding and coregulator displacement assays. |
N1C3 |
AB Vector LLC |
50 ug |
EUR 720 |
|
Description: Drug discovery, Nuclear receptors, purified recombinant protein |
LXRB-LBD. Purified GST-tagged human Liver X receptor beta ligand binding domain. Applications: Ligand-binding and coregulator displacement assays. |
N1H2 |
AB Vector LLC |
50 ug |
EUR 498 |
|
Description: Drug discovery, Nuclear receptors, purified recombinant protein |
LXRA-LBD. Purified GST-tagged human Liver X receptor alpha ligand binding domain. Applications: Ligand-binding and coregulator displacement assays. |
N1H3 |
AB Vector LLC |
50 ug |
EUR 360 |
|
Description: Drug discovery, Nuclear receptors, purified recombinant protein |
FXR-LBD. Purified GST-tagged human Farnesoid X receptor ligand binding domain. Applications: Ligand-binding and coregulator displacement assays. |
N1H4 |
AB Vector LLC |
50 ug |
EUR 360 |
|
Description: Drug discovery, Nuclear receptors, purified recombinant protein |
RXRA-LBD. Purified GST-tagged human Retinoid X receptor alpha ligand binding domain. Applications: Ligand-binding and coregulator displacement assays. |
N2B1 |
AB Vector LLC |
50 ug |
EUR 360 |
|
Description: Drug discovery, Nuclear receptors, purified recombinant protein |
RXRB-LBD. Purified GST-tagged human Retinoid X receptor beta ligand binding domain. Applications: Ligand-binding and coregulator displacement assays. |
N2B2 |
AB Vector LLC |
50 ug |
EUR 360 |
|
Description: Drug discovery, Nuclear receptors, purified recombinant protein |
RXRG-LBD. Purified GST-tagged human Retinoid X receptor gamma ligand binding domain. Applications: Ligand-binding and coregulator displacement assays. |
N2B3 |
AB Vector LLC |
50 ug |
EUR 360 |
|
Description: Drug discovery, Nuclear receptors, purified recombinant protein |
ERb-LBD. Purified GST-tagged human Estrogen receptor beta LBD. Applications: Ligand-binding and coregulator displacement assays. |
N3A2 |
AB Vector LLC |
50 ug |
EUR 495 |
|
Description: Drug discovery, Nuclear receptors, purified recombinant protein |
ESRRA-LBD. Purified GST-tagged human Estrogen-related receptor alpha ligand binding domain. Applications: Ligand-binding and coregulator displacement assays. |
N3B1 |
AB Vector LLC |
50 ug |
EUR 980 |
|
Description: Drug discovery, Nuclear receptors, purified recombinant protein |
ESRRB-LBD. Purified GST-tagged human Estrogen-related receptor beta ligand binding domain. Applications: Ligand-binding and coregulator displacement assays. |
N3B2 |
AB Vector LLC |
50 ug |
EUR 498 |
|
Description: Drug discovery, Nuclear receptors, purified recombinant protein |
ESRRG-LBD. Purified GST-tagged human Estrogen-related receptor gamma ligand binding domain. Applications: Ligand-binding and coregulator displacement assays. |
N3B3 |
AB Vector LLC |
50 ug |
EUR 360 |
|
Description: Drug discovery, Nuclear receptors, purified recombinant protein |
BV-Tau412. Recombinant baculovirus expressing 412 aa Tau isoform. |
PD13 |
AB Vector LLC |
1 ml |
EUR 899 |
|
Description: Drug discovery, Protein folding diseases, baculovirus |
BV-Tau412TR. Recombinant baculovirus expressing 412 aa Tau isoform. T39-R mutant. |
PD14 |
AB Vector LLC |
1 ml |
EUR 899 |
|
Description: Drug discovery, Protein folding diseases, baculovirus |
BV-Tau412KE. Recombinant baculovirus expressing 412 aa Tau isoform. K267-E mutant. |
PD15 |
AB Vector LLC |
1 ml |
EUR 899 |
|
Description: Drug discovery, Protein folding diseases, baculovirus |
BV-Synuclein. Recombinant baculovirus expressing alpha synuclein. |
PD17 |
AB Vector LLC |
1 ml |
EUR 899 |
|
Description: Drug discovery, Protein folding diseases, baculovirus |
BV-Syn-GFP. Recombinant baculovirus expressing alpha synuclein-GFP fusion. |
PD21 |
AB Vector LLC |
1 ml |
EUR 899 |
|
Description: Drug discovery, Protein folding diseases, baculovirus |
BV-SOD1. Recombinant baculovirus expressing SOD1. |
PD25 |
AB Vector LLC |
1 ml |
EUR 899 |
|
Description: Drug discovery, Protein folding diseases, baculovirus |
BV-SOD1-GFP. Recombinant baculovirus expressing SOD1-GFP fusion. |
PD29 |
AB Vector LLC |
1 ml |
EUR 899 |
|
Description: Drug discovery, Protein folding diseases, baculovirus |
BV-Tau352. Recombinant baculovirus expressing 352 aa Tau isoform. |
PD3 |
AB Vector LLC |
1 ml |
EUR 899 |
|
Description: Drug discovery, Protein folding diseases, baculovirus |
BV-Tau383. Recombinant baculovirus expressing 383 aa Tau isoform. |
PD7 |
AB Vector LLC |
1 ml |
EUR 899 |
|
Description: Drug discovery, Protein folding diseases, baculovirus |
BV-Tau381. Recombinant baculovirus expressing 381 aa Tau isoform. |
PD9 |
AB Vector LLC |
1 ml |
EUR 899 |
|
Description: Drug discovery, Protein folding diseases, baculovirus |
BV-PR-LBD. Recombinant baculovirus expressing Progesterone receptor LBD. |
S15 |
AB Vector LLC |
1 ml |
EUR 1250 |
|
Description: Drug discovery, Nuclear receptors, baculovirus |
BV-MR-LBD. Recombinant baculovirus expressing Mineralocorticoid receptor LBD. |
S27 |
AB Vector LLC |
1 ml |
EUR 1250 |
|
Description: Drug discovery, Nuclear receptors, baculovirus |
MR-LBD. Purified GST-tagged MR LBD in complex with Hsp90. Applications: Ligand-binding and coregulator displacement assays. |
S28 |
AB Vector LLC |
50 ug |
EUR 1240 |
|
Description: Drug discovery, Nuclear receptors, purified recombinant protein |
BV-GR-LBD. Recombinant baculovirus expressing Glucocorticoid receptor LBD. |
S33 |
AB Vector LLC |
1 ml |
EUR 1250 |
|
Description: Drug discovery, Nuclear receptors, baculovirus |
BV-GR. Recombinant baculovirus expressing Glucocorticoid receptor. |
S35 |
AB Vector LLC |
1 ml |
EUR 1250 |
|
Description: Drug discovery, Nuclear receptors, baculovirus |
BV-PXR-LBD. Recombinant baculovirus expressing Pregnane X receptor LBD. |
S36 |
AB Vector LLC |
1 ml |
EUR 1250 |
|
Description: Drug discovery, Nuclear receptors, baculovirus |
BV-AhR. Recombinant baculovirus expressing Aryl hydrocarbon receptor LBD. |
S41 |
AB Vector LLC |
1 ml |
EUR 1250 |
|
Description: Drug discovery, Nuclear receptors, baculovirus |
AhR-LBD. Purified GST-tagged human Arylhydrocarbon receptor LBD in complex with Hsp90. Applications: Ligand-binding and coregulator displacement assays. |
SAh90 |
AB Vector LLC |
50 ug |
EUR 980 |
|
Description: Drug discovery, Nuclear receptors, purified recombinant protein |
CAR. Purified GST-tagged human Constitutive andristane receptor in complex with Hsp90. Applications: Ligand-binding and coregulator displacement assays. |
SC90 |
AB Vector LLC |
50 ug |
EUR 1100 |
|
Description: Drug discovery, Nuclear receptors, purified recombinant protein |
ERa-LBD (Hsp90). Purified GST-tagged human Estrogen receptor alpha LBD in complex with Hsp90. Applications: Ligand-binding and coregulator displacement assays. |
SEa90 |
AB Vector LLC |
50 ug |
EUR 1100 |
|
Description: Drug discovery, Nuclear receptors, purified recombinant protein |
ERb-LBD (Hsp90). Purified GST-tagged human Estrogen receptor beta LBD in complex with Hsp90. Applications: ligand-binding and coregulator displacement studies. |
SEb90 |
AB Vector LLC |
50 ug |
EUR 760 |
|
Description: Drug discovery, Nuclear receptors, purified recombinant protein |
GR-LBD. GR-LBD. Purified GST-tagged human Estrogen receptor alpha LBD in complex with Hsp90. For ligand-binding and coregulator displacement studies. |
SG90 |
AB Vector LLC |
50 ug |
EUR 1240 |
|
Description: Drug discovery, Nuclear receptors, purified recombinant protein |
PR-LBD. Purified GST-tagged human Progesterone receptor LBD in complex with Hsp90. Applications: Ligand-binding and coregulator displacement assays. |
SP90 |
AB Vector LLC |
50 ug |
EUR 498 |
|
Description: Drug discovery, Nuclear receptors, purified recombinant protein |
PXR-LBD. Purified GST-tagged human Pregnane X receptor in complex with Hsp90. Applications: Ligand-binding and coregulator displacement assays. |
SPX90 |
AB Vector LLC |
50 ug |
EUR 498 |
|
Description: Drug discovery, Nuclear receptors, purified recombinant protein |
ProFectin. Transfection reagent for insect cells. |
T10 |
AB Vector LLC |
50 ul |
EUR 160 |
|
Description: Transfection |
ProFectin. Transfection reagent for insect cells. |
T20 |
AB Vector LLC |
100 ul |
EUR 295 |
|
Description: Transfection |
BbsI Linearized iLenti siRNA Vector |
LV014 |
ABM |
25 μl |
EUR 425 |
BbsI Linearized iLenti GFP siRNA Vector |
LV016 |
ABM |
25 μl |
EUR 425 |
AIF |
E8ET1603-4 |
EnoGene |
100ul |
EUR 275 |
Description: Available in various conjugation types. |
AIF1 siRNA |
20-abx907087 |
Abbexa |
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AIF1 siRNA |
20-abx907088 |
Abbexa |
-
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Isolates were tested for susceptibility to a variety of antimicrobial agents. Drinking unboiled water (odds ratio [OR] = 4.0, confidence interval [CI] = 1.8-7.5), drinking a beverage from a street vendor (OR = 2.8, CI = 1.3-5.9), eating raw seafood (OR = 3.4, CI = 1.4-11.5), and eating cooked crab (OR = 5.1, CI = 1.4-19.2) were associated with illness. Always boiling drinking water at home (OR = 0.5, CI = 0.2-0.9) was protective against illness. The presence of soap in either the kitchen (OR = 0.3, CI = 0.2-0.8) or bathroom (OR = 0.4, CI = 0.2-0.9) at home was also protective. V. cholerae O 1 was recovered from a pooled sample of a bivalve mollusc and from 68% of stool samples from case-patients. Thirty-six percent of the isolates from stool specimens were resistant to multiple antimicrobial agents.
Specific prevention measures may prevent transmission through these vehicles in the future. The appearance of antimicrobial resistance suggests the need for changes in current methods of prevention and treatment.